A procedure in which fecal matter from a healthy donor is transplanted into a patient’s gastrointestinal (GI) tract to restore healthy gut microbiota.

The transplanted stool introduces beneficial bacteria that help rebalance the gut microbiome, which can be disrupted by infections or antibiotics.

Common Uses / Indications

Primary use: Treat recurrent or severe Clostridium difficile (C. difficile) infection

Often occurs after antibiotic therapy or in patients with chronic GI conditions (e.g., inflammatory bowel disease)

Symptoms: diarrhea (sometimes with blood), abdominal cramping

Eligibility:

Patients with recurrent C. difficile infection after standard antibiotic treatments (e.g., metronidazole, vancomycin)

Other uses: Currently experimental; not routinely performed for other conditions