A specialized test that measures both acid reflux (pH changes) and non-acid reflux (movement of liquid/gas) in the esophagus using a thin catheter with multiple sensors.

Mechanism:

A catheter with pH and impedance sensors is placed through the nose into the esophagus.

pH sensors detect acid exposure.

Impedance sensors measure movement of fluid, gas, or mixed reflux regardless of acidity.

Together, they record reflux events and their correlation with symptoms.

Common Uses / Indications
Diagnosing gastroesophageal reflux disease (GERD), especially in patients with persistent symptoms despite therapy.

Distinguishing acid vs. non-acid reflux.

Evaluating patients with:

Atypical symptoms (chronic cough, hoarseness, chest pain)

Symptoms not responding to proton pump inhibitors (PPIs)

Pre-operative evaluation before anti-reflux surgery.